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April 2005
Volume 2, Issue 1
MGH Neurosurgical Society Alumni News






The functional and stereotactic neurosurgery program will be featured in the next alumni Newsletter


"I have great role models…the whole environment fosters the development of young investigator-clinicians."

Current Issue: [MS Word TM version] [Adobe Acrobat TM version]

Neurosurgery Alumni News MGH Neurosurgical Society Alumni HomePage
Dr. Emad N. Eskandar Director of Functional and Stereotactic Neurosurgery
Dr. Emad N. Eskandar is the new Director of Functional and Stereotactic Neurosurgery at MGH.

After completing his residency at Mass General in 1999, Dr. Eskandar joined the clinical faculty as an Assistant in Neurosurgery.

He is a leader, both in his clinical endeavors, and as a Principal Investigator at the MGH Laboratory for Sensorimotor Integration. Dr. Eskandar's work focuses on the functional circuitry involved in motor control in

order to provide better treatment for Parkinson's disease and other movement disorders.

Dr. Eskandar is eager to expand and develop the functional and stereotactic neurosurgery program. He notes: "It's exciting to work in MGH Neurosurgery, where there is such a rich opportunity for research that can help to improve our patients lives.

"The support that I receive here is unparalleled." said Dr. Eskandar

Dr. William Curry Joins Faculty, receives NREF Grant
Dr. William T. Curry, Jr. who completed his residency at MGH in 2002, has won an NREF Young Clincian's Award for 2005. The award was created by the Neurosurgery Research and Education Foundation of the AANS in 1985 to support rising clinician-investigators by funding pilot studies. Dr. Curry joined the MGH staff in 2003, and is researching the development of novel biological and immunologic therapies for malignant glioma.

"Overcoming immunological tolerance to tumor cells is the ultimate goal of cancer immunotherapy," said Dr. Curry, adding "Low levels of tumor-cell MHC and an immunosuppressive tumor microenvironment allow the growth of cancer cells that escape innate immunity. G207 (engineered by Dr. Martuza and collaborators) is a multimutated replication- conditional herpes simplex-1 that selectively replicates in tumor cells, has attenuated neurovirulence, and

Dr. Jeffrey Macklis receives Senator Javits Award
The National Institutes of Neurological Disorders and Stroke (NINDS) has awarded one of eight Senator Jacob Javits Award in the Neurosciences to Jeffrey D. Macklis, HMS Associate Professor of Neurology at Massachusetts General Hospital. Macklis will receive seven years of funding from the NINDS, a component of the National Institutes of Health.

Dr. Macklis has made significant contributions to the understanding of neuronal replacement and cellular repair of the brain following injury. His research shows that, contrary

to previously held beliefs, the reconstruction of complex networks in the brain's cerebral cortex can be achieved in adulthood. He hopes to identify the best conditions for the integration of neurons into existing networks of the
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